Business Type:Manufacturer
Country/Region:China
Ddu Verified
HOT Rank
8/10
Shanghai TheraMabs Bio-technology co., LTD
We are professional supplier in antibodies and fusion proteins,such as Pembrolizumab, Nivolumab, Transtuzumab,etc.
Business Type:Manufacturer
Country/Region:China
Ddu Verified
HOT Rank
8/10
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Description
LUCENTIS® (ranibizumab) is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment designed for intraocular use. Ranibizumab binds to and inhibits the biologic activity of human vascular endothelial growth factor A (VEGF-A). Ranibizumab, which lacks an Fc region, has a molecular weight of approximately 48 kilodaltons and is produced by an E. coli expression system in a nutrient medium containing the antibiotic tetracycline. Tetracycline is not detectable in the final product.
Ranibizumab is supplied at a concentration of 10 mg/mL as a sterile, colorless to pale yellow solution, which contains 10 mM histidine HCl, 10% α,α-trehalose dihydrate, 0.01% polysorbate 20, pH 5.5.
Properties
Name | Ranibizumab |
CAS NO. | 347396-82-1 |
Type | Fab fragment |
Source | Humanized (from mouse) |
Target | VEGF-A |
Clone | Monoclone |
Molecular Weight | 48 kDa |
Formula | C2158H3282N562O681S12 |
Antibody Form | Purified immunoglobulin |
Physical Form | Solution |
Grade Standard | Medicine Grade |
Place of Origin | China(Mainland) |
Storage | -70±15℃ for long-term storage, 2-8℃ for short-term storage, away from light. |
Supply Ability
20 kilogram per year, 1 Gram(Min. Order).
Material Safety Data Sheet
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Certificate Of Analysis
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Detail information about the product please refer the website below:
https://en.wikipedia.org/wiki/Ranibizumab