Shanghai TheraMabs Bio-technology co., LTD
We are professional supplier in antibodies and fusion proteins,such as Pembrolizumab, Nivolumab, Transtuzumab,etc.
Business Type:Manufacturer
Country/Region:China
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Description
Enbrel (etanercept), a tumor necrosis factor (TNF) blocker, is a dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1. Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids and has an apparent molecular weight of approximately 150 kilodaltons.
Etanercept is supplied at a concentration of 25 mg/mL as a sterile, preservative-free, clear, colorless solution, which contains 25 mM L-arginine hydrochloride,100 mM sodium chloride, 25 mM sodium phosphate, 1% sucrose.
Properties
Name | Etanercept |
CAS NO. | 185243-69-0 |
Type | A dimeric fusion protein |
Source | Human |
Target | TNF receptor |
Clone | Monoclone |
Molecular Weight | 150 kDa |
Formula | C2224H3475N621O698S36 |
Antibody Form | Purified immunoglobulin |
Physical Form | Solution |
Grade Standard | Medicine Grade |
Place of Origin | China(Mainland) |
Storage | -70±15℃ for long-term storage, 2-8℃ for short-term storage, away from light. |
Supply Ability
20 kilogram per year, 1 Gram（Min. Order）.
Material Safety Data Sheet
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Certificate Of Analysis
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Detail information about the product please refer the website below:
https://en.wikipedia.org/wiki/Etanercept
